Manuf: Bayer, Italy
Packaging: 30g vanishing cream in tube
Azelaic acid may be useful as a hair growth stimulant. A research report by Stamatiadis in 1988 suggested that azelaic acid (and combinations of it, with zinc ion and vitamin B6) was a strong type I 5-alpha reductase (5-AR) inhibitor. The enzyme, 5-AR (both Types I and II) convert testosterone to dihydrotestosterone (DHT). DHT has been shown to contribute to prostate enlargement (benign prostatic hyperplasia, BPH) and to damage hair follicles. Azelaic acid, used by itself, has been found to stimulate hair growth so may be used with or without topical Minoxidil (Regaine / Rogaine / Headway).
Azelaic acid is used as a topical treatment for mild to moderate acne . It is useful for both comedonal acne and inflammatory acne.
Azelaic acid is:
* Antibacterial - it reduces the growth of bacteria in the follicle (Proprionibacterium acnes and Staphylococcus epidermidis)
* Keratolytic & comedolytic - it returns to normal the disordered growth of the skin cells lining the follicle
* A scavenger of free radicals - i.e. it reduces inflammation.
Azelaic acid also helps reduce pigmentation, so it's particularly useful for darker skinned patients whose acne spots leave persistent brown marks or who have melasma.
The cream should be applied to the area affected by acne initially daily, then if tolerated building up to a generous twice-daily application after thoroughly cleansing the skin.
Acne responds slowly to treatment. Some improvement should be seen after one month of using azelaic acid cream. Further improvement should occur with maximum results after six months' continuous use. Treatment may be continued safely for months or years if the acne remains active.